The antiviral mechanism of viperin and its splice variant in spring viremia of carp virus infected fathead minnow cells

• Published in: Fish & shellfish immunology Vol. 86; pp. 805 - 813
• Main Authors: Wang, Fang, Jiao, Houqi, Liu, Wanmeng, Chen, Bo, Wang, Yeda, Chen, Buxin, Lu, Yuanan, Su, Jianguo, Zhang, Yongan, Liu, Xueqin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2019
• Subjects: Alternative splicing variant; FHM cells; Spring viremia of carp virus (SVCV); Viperin; Viperin; FHM cells; Alternative splicing variant; Spring viremia of carp virus (SVCV)

Viperin is known to play an important role in innate immune and its antiviral mechanisms are well demonstrated in mammals. Fish Viperin mediates antiviral activity against several viruses. However, little has been done to the underlying mechanism. Here, we discovered a novel Viperin splice variant n...