Cervical cancer biomarker screening based on Raman spectroscopy and multivariate statistical analysis

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 317; p. 124402
• Main Authors: Fan, Qiwen, Ding, Hongli, Mo, Huixia, Tang, Yishu, Wu, Guohua, Yin, Longfei
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 05.09.2024
• Subjects: Cervical cancer; Multivariate statistical analysis; Serum; Surface-enhanced Raman spectroscopy; Tumor markers; Serum; Tumor markers; Multivariate statistical analysis; Cervical cancer; Surface-enhanced Raman spectroscopy

[Display omitted] •Multivariate analysis methods were employed to establish diagnostic models.•PLS-DA demonstrated superior classification performance between cancer and normal individuals compared to PCA-SVM and OPLS-DA models.•A hybrid feature selection strategy incorporating PLS-DA and RF models...