Profiling of volatile organic compounds produced by clinical Aspergillus isolates using gas chromatography-mass spectrometry

• Published in: Medical mycology (Oxford) Vol. 56; no. 2; p. 253
• Main Authors: Gerritsen, M G, Brinkman, P, Escobar, N, Bos, L D, de Heer, K, Meijer, M, Janssen, H-G, de Cock, H, Wösten, H A B, Visser, C E, van Oers, M H J, Sterk, P J
• Format: Journal Article
• Language: English
• Published: England 01.02.2018
• Subjects: Aspergillus - classification; Aspergillus - isolation & purification; Aspergillus - metabolism; Breath Tests; Gas Chromatography-Mass Spectrometry; Humans; Invasive Pulmonary Aspergillosis - diagnosis; Invasive Pulmonary Aspergillosis - physiopathology; Volatile Organic Compounds - chemistry; Aspergillus; headspace analysis; gas chromatography-mass spectrometry; exhaled breath analysis; invasive pulmonary aspergillosis

Volatile organic compounds (VOCs) in exhaled breath may identify the presence of invasive pulmonary aspergillosis. We aimed to detect VOC profiles emitted by in vitro cultured, clinical Aspergillus isolates using gas chromatography-mass spectrometry (GC-MS). Three clinical Aspergillus isolates and a...