Epigenetic Regulation of the ERβ Gene on the Estrogen Signal Transfection Pathway in Colon Cancer Cells

• Published in: Journal of Huazhong University of Science and Technology. Medical sciences Vol. 30; no. 1; pp. 69 - 74
• Main Author: 翟荣林 王国斌 蔡开琳 陶凯雄 许飞 张万里 王智勇
• Format: Journal Article
• Language: English
• Published: Heidelberg Huazhong University of Science and Technology 01.02.2010; Department of General Surgery,Union Hospital,Tong]i Medical College,Huazhong University of Science and Technology,Wuhan430022,China
• Subjects: Medicine; Medicine & Public Health; signal transfection; methylation; colon cancer; epigenetics; estrogen receptor β

We studied the regulatory effects of the estragen receptorβ(ERβ)gene on the downstream estrogen signal transfection pathway in colon cancer cells and the possible mechanisms involved.A human ERβ gene recombinant expression plasmid,pEGFP-C1-ERβ,was constructed and transfected into the Caco-2 colon ca...