BWA-MEME: BWA-MEM emulated with a machine learning approach

• Published in: Bioinformatics (Oxford, England) Vol. 38; no. 9; pp. 2404 - 2413
• Main Authors: Jung, Youngmok, Han, Dongsu
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 28.04.2022

Abstract Motivation The growing use of next-generation sequencing and enlarged sequencing throughput require efficient short-read alignment, where seeding is one of the major performance bottlenecks. The key challenge in the seeding phase is searching for exact matches of substrings of short reads i...