Carboxylated aurone derivatives as potent inhibitors of xanthine oxidase
[Display omitted] •Carboxylated aurone derivatives are able to inhibit xanthine oxidase in vitro.•The inhibition efficiency of the aurone derivatives is higher than that of sulfuretin.•Modes of inhibitor binding to the enzyme active site are proposed. Xanthine oxidase is a potential target for treat...
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Published in | Bioorganic & medicinal chemistry Vol. 25; no. 14; pp. 3606 - 3613 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
OXFORD
Elsevier Ltd
15.07.2017
Elsevier |
Subjects | |
Online Access | Get full text |
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