Convenient regioselective reaction in presence of H3PW12O40: synthesis and characterization of pyrazolo[3,4-b]quinoline-3,5-diones

• Published in: Research on chemical intermediates Vol. 44; no. 2; pp. 873 - 882
• Main Authors: Zahedifar, Mahboobeh, Shojaei, Reza, Sheibani, Hassan
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.02.2018; Springer Nature; Springer Nature B.V
• Subjects: Aldehydes; Catalysis; Catalysts; Chemical synthesis; Chemistry; Chemistry and Materials Science; Chemistry, Multidisciplinary; Inorganic Chemistry; Pharmacology; Physical Chemistry; Physical Sciences; Quinoline; Regioselectivity; Science & Technology; Pyrazolo[3,4; Regioselectivity; quinoline-3,5-diones; 5-Aminopyrazolone; Poly tungstophosphoric acid; Pyrazolo[3,4-b]quinoline-3,5-diones; IN-VITRO; DERIVATIVES; KETENE

We describe regioselective synthesis of pyrazolo[3,4- b ]quinoline derivatives by multicomponent reaction of dimedone, 5-aminopyrazolone, and aromatic aldehydes in presence of H 3 PW 12 O 40 as catalyst. When this multicomponent reaction was investigated without catalyst under reflux conditions, a m...