Evaluation of interleukin 23 (IL-23) as a non-invasive test of disease severity in patients with ulcerative colitis

• Published in: Arab journal of gastroenterology Vol. 19; no. 3; pp. 116 - 120
• Main Authors: Youssef, Tarek, Saleh, Shereen A., Rund, Angie, Montasser, Iman, Mohsen, Manal, Hazem, Ola
• Format: Journal Article
• Language: English
• Published: Egypt Elsevier B.V 01.09.2018
• Subjects: Adult; Case-Control Studies; Colitis, Ulcerative - blood; Colitis, Ulcerative - pathology; Disease severity; Female; Humans; Interleukin 23 (IL-23); Interleukin-23 - blood; Male; Middle Aged; ROC Curve; Severity of Illness Index; Ulcerative colitis; Disease severity; Interleukin 23 (IL-23); Ulcerative colitis

Studies have found increased expression of IL-23 in inflamed and non-inflamed mucosa of patients with ulcerative colitis (UC). We hypothesized that serum interleukin-23 as a non-invasive test has a role in pathogenesis of ulcerative colitis disease and correlates with the disease severity. Forty pat...