The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy

• Published in: Future medicinal chemistry Vol. 6; no. 2; p. 205
• Main Authors: Ooi, Jenny Y Y, Bernardo, Bianca C, McMullen, Julie R
• Format: Journal Article
• Language: English
• Published: England 01.02.2014
• Subjects: Animals; Cardiomegaly - metabolism; Cardiomegaly - physiopathology; Cardiomegaly - therapy; Female; Heart - growth & development; Heart - physiology; Hepatitis C - therapy; MicroRNAs - antagonists & inhibitors; MicroRNAs - metabolism; MicroRNAs - therapeutic use; Physical Conditioning, Animal; Pregnancy; Signal Transduction

Cardiac hypertrophy is broadly defined as an increase in heart mass. Heart enlargement in a setting of cardiac disease is referred to as pathological hypertrophy and often progresses to heart failure. Physiological hypertrophy refers to heart growth in response to postnatal development, exercise tra...