In vivo Raman spectroscopy for non-invasive transcutaneous glucose monitoring on animal models and human subjects

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 329; p. 125584
• Main Authors: Liu, Jing, Chu, Jiahui, Xu, Jie, Zhang, Zhanqin, Wang, Shuang
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.03.2025
• Subjects: Adult; Animal model; Animals; Blood Glucose - analysis; Blood Glucose Self-Monitoring - methods; Female; Human subjects; Humans; Male; Mice; Neural network; Neural Networks, Computer; Non-invasive glucose monitoring; Raman spectroscopy; Spectrum Analysis, Raman - methods; Human subjects; Animal model; Neural network; Raman spectroscopy; Non-invasive glucose monitoring
• ISSN: 1386-1425; 1873-3557
• DOI: 10.1016/j.saa.2024.125584

[Display omitted] •In vivo Raman measurements were conducted on both mouse model and human subject for characterizing the glucose fingerprint.•Glucose fingerprint variations exhibited a strong correlation with the actual changes in blood glucose concentration.•Intraspectrum intensity ratio (I1125/I1...