Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania

• Published in: Clinica chimica acta Vol. 468; pp. 25 - 31
• Main Authors: Moritz, Eileen, Wegner, Danilo, Groß, Stefan, Bahls, Martin, Dörr, Marcus, Felix, Stephan B., Ittermann, Till, Oswald, Stefan, Nauck, Matthias, Friedrich, Nele, Böger, Rainer H., Daum, Günter, Schwedhelm, Edzard, Rauch, Bernhard H.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2017
• Subjects: Adult; Blood Chemical Analysis - standards; Female; Germany; Health Surveys; Humans; Lysophospholipids - blood; Male; Reference intervals; Sphingosine - analogs & derivatives; Sphingosine - blood; Sphingosine-1-phosphate; Study of Health in Pomerania; ALAT; BP; HDL; LC-MS/MS; QC; S1P; LDL; Sphingosine-1-phosphate; SHIP; CKD-EPI; HbA1c; HPLC; BMI; eGFR; ATC code; CI; CAD; IQR; Study of Health in Pomerania; Reference intervals; CVD; CV; GGT; FCS; ASAT

The bioactive signaling lipid sphingosine-1-phosphate (S1P) is a potential biomarker for cardiovascular disease (CVD). To date, no reference intervals for S1P have been defined. This study aims to establish a reference range for serum S1P in healthy individuals. We determined reference intervals for...