Ellagic and ferulic acids alleviate gamma radiation and aluminium chloride-induced oxidative damage

• Published in: Life sciences (1973) Vol. 160; pp. 2 - 11
• Main Authors: Salem, Ahmed M., Mohammaden, Tarek F., Ali, Mohamed A.M., Mohamed, Enas A., Hasan, Hesham F.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.09.2016
• Subjects: Aluminium chloride; Aluminum Compounds - pharmacology; Animals; Antioxidants - metabolism; Chlorides - pharmacology; Coumaric Acids - pharmacology; Ellagic acid; Ellagic Acid - pharmacology; Ferulic acid; Gamma radiation; Gamma Rays; Lipid Peroxidation; Lipids - blood; Male; Oxidative stress; Oxidative Stress - drug effects; Oxidative Stress - radiation effects; Rats; Rats, Sprague-Dawley; Oxidative stress; Aluminium chloride; Gamma radiation; Ellagic acid; Ferulic acid

Ionizing radiation interacts with biological systems through the generation of free radicals, which induce oxidative stress. Aluminium (Al) can negatively impact human health by direct interaction with antioxidant enzymes. Ellagic acid (EA) and Ferulic acid (FA) are plant polyphenolic compounds, hav...