Structure and topology of the linkers in the conserved lepidosaur β-keratin chain with four 34-residue repeats support an interfilament role for the central linker

• Published in: Journal of structural biology Vol. 212; no. 1; p. 107599
• Main Author: Parry, David A.D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2020
• Subjects: Lepidosaurs; Serine repeat motif; Topology of repeats and linkers; β-Keratin; Serine repeat motif; Topology of repeats and linkers; β-Keratin; Lepidosaurs

•The 20 topologies of the four 34-residue repeats and the three linkers are described.•A serine-X dipeptide repeat occurs in the central linker only.•A beta-sandwich in neighbouring filaments is connected by the central linker. The β-keratin chain with four 34-residue repeats that is conserved acros...