Genetic determinants of hepatic steatosis and serum cytokeratin‐18 fragment levels in Taiwanese children

• Published in: Liver international Vol. 38; no. 7; pp. 1300 - 1307
• Main Authors: Lin, Yu‐Cheng, Chang, Pi‐Feng, Chang, Mei‐Hwei, Ni, Yen‐Hsuan
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.07.2018
• Subjects: Acyltransferase; Adults; Apoptosis; Biomarkers; Body mass; Body mass index; Body size; Children; Cytokeratin; cytokeratin‐18; Fatty liver; Fragmentation; Genotypes; Insulin; Liver; Liver diseases; MBOAT7; nonalcoholic fatty liver disease; Proteins; Regression models; Risk analysis; Risk factors; Saline water; Serum levels; Steatosis; Ultrasonography; cytokeratin-18; nonalcoholic fatty liver disease; children; MBOAT7

Background/Aims There are substantial genetic components contributing to the susceptibility of nonalcoholic fatty liver disease (NAFLD). It has recently been reported that the rs641738 C>T variant in the membrane‐bound O‐acyltransferase domain‐containing protein 7 (MBOAT7) gene increased severity...