The functional interplay of lncRNA EGOT and HuR regulates hypoxia‐induced autophagy in renal tubular cells

• Published in: Journal of cellular biochemistry Vol. 121; no. 11; pp. 4522 - 4534
• Main Authors: Wang, I‐Kuan, Palanisamy, Kalaiselvi, Sun, Kuo‐Ting, Yu, Shao‐Hua, Yu, Tung‐Min, Li, Ching‐Hao, Lin, Feng‐Yen, Chou, An‐Kuo, Wang, Guei‐Jane, Chen, Kuen‐Bao, Li, Chi‐Yuan
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2020
• Subjects: acute kidney injury; Antigens; Autophagy; Cell survival; EGOT; HK‐2; HuR; HuR protein; Hypoxia; Kidneys; Leukocytes (eosinophilic); lncRNA; Ontogeny; Phagocytosis; Post-transcription; Ribonucleic acid; RNA; HK-2; acute kidney injury; autophagy; lncRNA; HuR; EGOT

Autophagy, an important cellular homeostatic mechanism regulates cell survival under stress and protects against acute kidney injury. However, the role of long noncoding RNA (lncRNA) in autophagy regulation in renal tubular cells (HK‐2) is unclear. The study was aimed to understand the importance of...