Alkalinized lidocaine solution as a first‐line local anesthesia protocol for intradetrusor injection of onabotulinum toxin A: Results from a double‐blinded randomized controlled trial

• Published in: Neurourology and urodynamics Vol. 39; no. 8; pp. 2471 - 2479
• Main Authors: Pereira e Silva, Ricardo, Ponte, Carolina, Lopes, Filipe, Palma dos Reis, José
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2020
• Subjects: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Anesthesia; anesthesia, local; Anesthetics, Local - administration & dosage; Bladder; botulinum toxins, type A; Botulinum Toxins, Type A - administration & dosage; Clinical trials; Double-Blind Method; Double-blind studies; Female; Hematuria; Humans; Injection; Lidocaine; Lidocaine - administration & dosage; Local anesthesia; Male; Middle Aged; Pain; Pain - drug therapy; Pain Measurement; randomized controlled trial; Sodium bicarbonate; Standardization; Urinary Bladder, Neurogenic - drug therapy; urinary bladder, overactive; Urinary tract; Urinary tract infections; Urological Agents - administration & dosage; double-blind method; botulinum toxins, type A; anesthesia, local; administration, intravesical; sodium bicarbonate; lidocaine; randomized controlled trial; urinary bladder, overactive

Aims Local anesthesia protocols for intradetrusor onabotulinum toxin A (BoNTA) injection lack standardization. We aimed to determine if an alkalinized lidocaine solution is more effective than lidocaine only. Methods Patients of both genders aged 18 or above enlisted for intradetrusor BoNTA injectio...