Serum bile acid profiles are associated with heart failure with preserved ejection fraction in patients with metabolic dysfunction‐associated fatty liver disease: An exploratory study

• Published in: Diabetes, obesity & metabolism Vol. 26; no. 9; pp. 3684 - 3695
• Main Authors: Zhou, Xiao‐Dong, Xu, Cui‐Fang, Chen, Qin‐Fen, Shapiro, Michael D., Lip, Gregory Y. H., Chen, Li‐Li, Targher, Giovanni, Byrne, Christopher D., Tian, Na, Xiao, Tie, Huang, Chen‐Xiao, Ni, Yan, Zheng, Ming‐Hua
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2024; Wiley Subscription Services, Inc
• Subjects: Acids; bile acids profile; Biopsy; Congestive heart failure; Echocardiography; Ejection fraction; Fatty liver; Heart diseases; Heart failure; heart failure with preserved ejection fraction; Liquid chromatography; Liver diseases; Mass spectroscopy; metabolic dysfunction‐associated fatty liver disease; Metabolism; Serum levels; Tauroursodeoxycholic acid; Ursodeoxycholic acid; Ventricle; metabolic dysfunction‐associated fatty liver disease; heart failure with preserved ejection fraction; bile acids profile

Aim To analyse the association between serum bile acid (BA) profile and heart failure (HF) with preserved ejection fraction (HFpEF) in patients with metabolic dysfunction‐associated fatty liver disease (MAFLD). Methods We enrolled 163 individuals with biopsy‐proven MAFLD undergoing transthoracic ech...