Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysis

• Published in: Scientific reports Vol. 6; no. 1; p. 33339
• Main Authors: Yang, Qihua, Huang, Tao, Ye, Guoliang, Wang, Bojun, Zhang, Xinjun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.09.2016; Nature Publishing Group
• Subjects: 45; 45/61; 45/77; 631/208/176/1988; 692/4028/67/1857; Benign; Colorectal cancer; Colorectal carcinoma; DNA methylation; Feces; Frizzled protein; Frizzled-related protein; Frizzled-related protein 1; Humanities and Social Sciences; Lesions; Meta-analysis; Methylation; Mucosa; multidisciplinary; Science; Signal transduction; Wnt protein

Methylation of secreted frizzled-related protein genes (SFRP) associated with the Wnt signaling pathway has previously been reported. However, the diagnostic role of SFRP methylation in colorectal cancer (CRC) remains unclear. A systematic search was performed to identify eligible articles for analy...