Whether Immunostimulants Are Effective in Susceptible Children Suffering From Recurrent Respiratory Tract Infections: A Modeling Analysis Based on Literature Aggregate Data

• Published in: Journal of clinical pharmacology Vol. 62; no. 2; p. 245
• Main Authors: Zhang, Weilong, Huang, Jihan, Liu, Hongxia, Wen, Xin, Zheng, Qingshan, Li, Lujin
• Format: Journal Article
• Language: English
• Published: England 01.02.2022
• Subjects: Adjuvants, Immunologic - administration & dosage; Adjuvants, Immunologic - adverse effects; Cell Extracts - administration & dosage; Cell Extracts - adverse effects; Child; Female; Humans; Male; Models, Biological; Pyrrolidonecarboxylic Acid - administration & dosage; Pyrrolidonecarboxylic Acid - adverse effects; Pyrrolidonecarboxylic Acid - analogs & derivatives; Respiratory Tract Infections - prevention & control; Thiazolidines - administration & dosage; Thiazolidines - adverse effects; immunostimulants; modeling and simulation, recurrent respiratory tract infections

Immunostimulants are gradually being used in the prevention and treatment of recurrent respiratory tract infections in susceptible children, but their drug effects have not been quantified. The purpose of this study was to confirm the efficacy of immunostimulants in the prevention and treatment of r...