Merkel cell carcinoma in situ: A systematic review of prognosis and management

• Published in: Australasian journal of dermatology Vol. 63; no. 1; pp. e6 - e12
• Main Authors: Truong, Kelvin, Goldinger, Simone M, Chou, Shaun, Howle, Julie R, Veness, Michael J, Fernandez‐Peñas, Pablo, Varey, Alexander H R
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.02.2022
• Subjects: Biopsy; carcinoma in situ; Carcinoma in Situ - mortality; Carcinoma in Situ - pathology; Carcinoma in Situ - therapy; Carcinoma, Merkel Cell - mortality; Carcinoma, Merkel Cell - pathology; Carcinoma, Merkel Cell - therapy; Case reports; Clinical trials; Humans; intraepidermal merkel cell carcinoma; Invasiveness; Literature reviews; Lymph nodes; Lymphatic system; management; Medical prognosis; merkel cell carcinoma; merkel cell carcinoma in situ; Neuroendocrine tumors; Prognosis; Radiation therapy; Skin Neoplasms - mortality; Skin Neoplasms - pathology; Skin Neoplasms - therapy; Systematic review; carcinoma in situ; merkel cell carcinoma in situ; merkel cell carcinoma; management; intraepidermal merkel cell carcinoma; systematic review; prognosis

Background Merkel cell carcinoma (MCC) is a rare primary cutaneous neuroendocrine tumour. While dermally invasive MCC is known to have a five‐year survival of only 30‐40%, the prognosis and management of MCC in situ (MCCis) is not widely reported. Objective We present a systematic review to elucidat...