Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk

• Published in: Journal of periodontal research Vol. 58; no. 1; pp. 165 - 174
• Main Authors: Isola, Gaetano, Santonocito, Simona, Distefano, Alfio, Polizzi, Alessandro, Vaccaro, Manuel, Raciti, Giuseppina, Alibrandi, Angela, Li Volti, Giovanni
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2023
• Subjects: C-reactive protein; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - genetics; Epigenetics; gingival crevicular fluid; Gingival Crevicular Fluid - chemistry; Gum disease; Humans; Inflammation; microRNA; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; miRNA; Oxidative Stress; Periodontitis; Periodontitis - genetics; Periodontitis - metabolism; Polymerase chain reaction; Sampling; gingival crevicular fluid; cardiovascular disease; microRNA; oxidative stress; c-reactive protein; periodontitis

Background and Objective Recent emerging evidence has shown that microRNA (miRNAs) is involved in several epigenetic processes linked with periodontitis, increased oxidative stress and cardiovascular disease (CVD). The present study aimed to assess the impact of periodontitis on gingival crevicular...