Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects - Han, Sungpil; Choi, Hee Youn; Kim, Yo Han; Nam, Ji Yeon; Kim, Bongtae; Song, Geun Seog; Lim, Hyeong‐Seok; Bae, Kyun‐Seop (Alimentary pharmacology & therapeutics, 2019)
Keywords: Acids; Administration, Oral; Adult; Benzene Derivatives - administration & dosage; Clinical trials; Complications; Dosage; Dose-Response Relationship, Drug; Double-Blind Method; Esomeprazole - administration & dosage; Esophagus; Gastric Acid - metabolism; Gastric juice; Gastroesophageal reflux; H(+)-K(+)-Exchanging ATPase - metabolism; Health risk assessment; Helicobacter pylori; Humans; Imidazoles - administration & dosage; Male; Middle Aged; Omeprazole; Pharmacodynamics; Pharmacokinetics; Potassium; Safety; Urine; Young Adult