Exosomal tumor necrosis factor‐α from hepatocellular cancer cells (Huh‐7) promote osteoclast differentiation - Li, Ching‐Hao; Palanisamy, Kalaiselvi; Li, Xin; Yu, Shao‐Hua; Wang, I‐Kuan; Li, Chi‐Yuan; Sun, Kuo‐Ting (Journal of cellular biochemistry, 2021)
Keywords: Animals; Biomedical materials; Bone cancer; Bone diseases; Bone growth; Bone resorption; Cathepsin K; Cathepsin K - metabolism; CD63 antigen; Cell differentiation; Cell Differentiation - physiology; Cell interactions; Cellular communication; Culture Media, Conditioned - pharmacology; Exosomes; Exosomes - metabolism; Exosomes - pathology; hepatocellular cancer; Hepatocytes; Humans; inflammation; Liver cancer; Liver Neoplasms - pathology; Markers; Metastases; Mice; Necrosis; NF-kappa B - metabolism; Osteoclastogenesis; Osteoclasts; Osteoclasts - cytology; Osteolysis; pathological fracture; RAW 264.7 Cells; Regulatory mechanisms (biology); Tartrate-Resistant Acid Phosphatase - metabolism; Therapeutic targets; TRAF6 protein; tumor necrosis factor ɑ; Tumor Necrosis Factor-alpha - metabolism; Tumor Necrosis Factor-alpha - pharmacology; Tumor necrosis factor-TNF; Tumor necrosis factor-α; tumor necrosis factor ɑ; inflammation; hepatocellular cancer; exosomes; pathological fracture