MicroRNA‐30b regulates insulin sensitivity by targeting SERCA2b in non‐alcoholic fatty liver disease

• Published in: Liver international Vol. 39; no. 8; pp. 1504 - 1513
• Main Authors: Dai, Li‐Li, Li, Shu‐De, Ma, Yi‐Cheng, Tang, Jun‐Rui, Lv, Jun‐Yan, Zhang, Yuan‐Qing, Miao, Ying‐Lei, Ma, Yan‐Qiong, Li, Chun‐Mei, Chu, Yi‐You, Wang, Kun‐Hua, Ma, Lan‐Qing, Zou, Cheng‐Gang
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.08.2019
• Subjects: Adenosine triphosphatase; Algorithms; Biomarkers; Ca2+-transporting ATPase; Calcium; Calcium ions; Diet; Disease resistance; DNA microarrays; Endoplasmic reticulum; endoplasmic reticulum stress; Fatty liver; High fat diet; Human subjects; In vivo methods and tests; Insulin; Insulin resistance; Liver; Liver diseases; microRNA; MicroRNAs; miRNA; NAFLD; Obesity; Ribonucleic acid; RNA; Steatosis; Stress; Target recognition; microRNA; NAFLD; insulin resistance; endoplasmic reticulum stress

Background & Aims Insulin resistance is strongly associated with non‐alcoholic fatty liver disease, a chronic, obesity–related liver disease. Increased endoplasmic reticulum (ER) stress plays an important role in the development of insulin resistance. In this study, we investigated the roles of...