Intracellular Staphylococcus aureus and host cell death pathways

• Published in: Cellular microbiology Vol. 23; no. 5; pp. e13317 - n/a
• Main Authors: Soe, Ye Mon, Bedoui, Sammy, Stinear, Timothy P., Hachani, Abderrahman
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Inc 01.05.2021
• Subjects: Antibiotics; Apoptosis; Autophagy; Cell death; Commensalism; ferroptosis; Intracellular; intracellular pathogen; Localization; metabolism; Necroptosis; Opportunist infection; Pathogenesis; PCD; Penicillin; Phagocytosis; programmed cell death; Pyroptosis; Staphylococcus aureus; Virulence; Virulence factors; PCD; pyroptosis; autophagy; ferroptosis; intracellular pathogen; apoptosis; metabolism; programmed cell death; Staphylococcus aureus; necroptosis

Staphylococcus aureus is a major opportunistic human pathogen that is globally prevalent. Although S. aureus and humans may have co‐evolved to the point of commensalism, the bacterium is equipped with virulence factors causing devastating infections. The adoption of an intracellular lifestyle by S....