Endothelin activation and postoperative renal failure after human liver transplantation

• Published in: Liver transplantation Vol. 11; no. 10; pp. 1201 - 1206
• Main Authors: Hetz, Hubert, Bauer, Michael, Lahner, Daniel, Faybik, Peter, Winning, Johannes, Ankersmit, Hendrik Jan, Bacher, Andreas, Krenn, Claus Georg
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.10.2005
• Subjects: Endothelins - physiology; Female; Glomerular Filtration Rate; Humans; Liver Transplantation - adverse effects; Male; Middle Aged; Postoperative Complications - epidemiology; Renal Insufficiency - epidemiology; Treatment Failure

Renal failure is an established risk factor for impaired patient outcome after orthotopic liver transplantation (OLT). As the endothelin pathway is known to be involved in the development of acute renal failure (ARF), we designed a study to clarify its role in ARF following OLT. Twenty consecutive p...