Reduction in Spinal Radiographic Progression in Ankylosing Spondylitis Patients Receiving Prolonged Treatment With Tumor Necrosis Factor Inhibitors

• Published in: Arthritis care & research (2010) Vol. 69; no. 7; pp. 1011 - 1019
• Main Authors: Maas, Fiona, Arends, Suzanne, Brouwer, Elisabeth, Essers, Ivette, van der Veer, Eveline, Efde, Monique, van Ooijen, Peter M. A., Wolf, Rinze, Veeger, Nic J. G. M., Bootsma, Hendrika, Wink, Freke R., Spoorenberg, Anneke
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.07.2017
• Subjects: Adult; Ankylosing spondylitis; Anti-Inflammatory Agents - administration & dosage; Body mass; Body mass index; Cohort Studies; Disease Progression; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Mathematical models; Middle Aged; Patients; Prospective Studies; Radiography; Radiography - trends; Random Allocation; Sensitivity analysis; Smoking; Spine; Spine - diagnostic imaging; Spondylitis; Spondylitis, Ankylosing - diagnostic imaging; Spondylitis, Ankylosing - drug therapy; TNF inhibitors; Treatment Outcome; Tumor necrosis factor; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor necrosis factor-TNF

Objective To evaluate the course of spinal radiographic progression for up to 8 years of followup in a large cohort of ankylosing spondylitis (AS) patients treated with tumor necrosis factor (TNF) inhibitors. Methods Consecutive patients from the Groningen Leeuwarden AS cohort starting TNF inhibitor...