Autoantibodies in Prediction of the Development of Rheumatoid Arthritis Among Healthy Relatives of Patients With the Disease

• Published in: Arthritis & rheumatology (Hoboken, N.J.) Vol. 67; no. 11; pp. 2837 - 2844
• Main Authors: Ramos‐Remus, Cesar, Castillo‐Ortiz, Jose Dionisio, Aguilar‐Lozano, Luis, Padilla‐Ibarra, Jorge, Sandoval‐Castro, Carlos, Vargas‐Serafin, Cesar Omar, de la Mora‐Molina, Hector, Ramos‐Gomez, Ariadna, Sanchez‐Ortiz, Adriana, Avila‐Armengol, Hilario, Aceves‐Avila, Francisco Javier
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2015
• Subjects: Adult; Arthritis, Rheumatoid - blood; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - immunology; Autoantibodies - blood; Female; Humans; Immunoglobulin M - blood; Male; Middle Aged; Peptides, Cyclic - immunology; Rheumatoid Factor - immunology; Surveys and Questionnaires; Young Adult

Objective Although blood bank–based studies have shown that rheumatoid arthritis (RA)–related autoantibodies are present before the onset of RA, information on their positive predictive value (PPV) for development of RA in healthy individuals is scarce. This study was undertaken to assess the 5‐year...