An integrative analysis of genome‐wide methylation and expression in ameloblastoma: A pilot study

• Published in: Oral diseases Vol. 27; no. 6; pp. 1455 - 1467
• Main Authors: Pongpanich, Monnat, Sanguansin, Sirima, Kengkarn, Sudaporn, Chaiwongkot, Arkom, Klongnoi, Boworn, Kitkumthorn, Nakarin
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.09.2021
• Subjects: Ameloblastoma; Ameloblastoma - genetics; CpG Islands; Deoxyribonucleic acid; DNA; DNA Methylation; Fibroblast growth factor receptor 2; Follicles; Gene expression; Genomes; Humans; integrative analysis; Jaw; Neoplasm Recurrence, Local; Pilot Projects; Tumorigenesis; DNA methylation; integrative analysis; gene expression; ameloblastoma

Objective DNA methylation regulates the expression of various genes involved in tumorigenesis. Ameloblastoma is a benign odontogenic jaw tumor. It is locally aggressive with a high level of recurrence. A delay in treatment can lead to severe facial disfigurement. To the best of our knowledge, this i...