Angiotensin‐converting enzyme gene polymorphism and digestive system cancer risk: A meta‐analysis based on 9656 subjects

• Published in: Journal of cellular biochemistry Vol. 120; no. 12; pp. 19388 - 19395
• Main Authors: Abdeahad, Hossein, Avan, Amir, Khazaei, Majid, Soleimanpour, Saman, Ferns, Gordon A., Fiuji, Hamid, Ryzhikov, Mikhail, Bahrami, Afsane, Hassanian, Seyed Mahdi
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2019
• Subjects: ACE protein; Angiotensin; angiotensin‐converting enzyme; Cancer; Colorectal cancer; Colorectal carcinoma; Confidence intervals; Conversion; Digestive system; Enzymes; Gastric cancer; Gastrointestinal tract; Gene deletion; Gene polymorphism; Health risks; Insertion; Medical prognosis; Meta-analysis; Polymorphism; Renin; Renin‐angiotensin system; Risk analysis; Statistical analysis; Subgroups; colorectal cancer; gastric cancer; Renin-angiotensin system; angiotensin-converting enzyme

The angiotensin‐converting enzyme (ACE) is the major regulator of the renin‐angiotensin system, and it has been reported that genetic polymorphisms at this locus are associated with risk in numerous types of human cancers. In the current meta‐analysis, we aimed to evaluate the association between th...