Zona pellucida glycoproteins: Relevance in fertility and development of contraceptive vaccines

• Published in: American journal of reproductive immunology (1989) Vol. 89; no. 2; pp. e13535 - n/a
• Main Author: Gupta, Satish K.
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.02.2023
• Subjects: Animals; B cell epitope mapping; Contraception, Immunologic; contraceptive vaccine; Deer; Dogs; Dystrophy; Egg Proteins - genetics; Egg Proteins - metabolism; Epitopes; Epitopes, B-Lymphocyte - metabolism; Female; Fertility; Fertilization; Follicular Atresia; Glycoproteins; Horses; Humans; Immunization; Infertility; Lymphocytes T; Lyssavirus; Membrane Glycoproteins; Monoclonal antibodies; Oocytes; Ovaries; Rabies; Receptors, Cell Surface - metabolism; Recombinant Proteins; Vaccines; Vaccines, Contraceptive; wildlife population management; Zona Pellucida; zona pellucida glycoproteins; Zona Pellucida Glycoproteins - metabolism; Zoonoses; contraceptive vaccine; zona pellucida glycoproteins; infertility; B cell epitope mapping; wildlife population management

Mammalian zona pellucida (ZP) is composed of three to four glycoproteins, which plays an important role during fertilization. Mutations in the genes encoding zona proteins are reported in women with empty follicle syndrome, degenerated oocytes and those with an abnormal or no ZP further emphasizing...