Diagnostic cut‐off of Aspergillus fumigatus‐specific IgG in the diagnosis of chronic pulmonary aspergillosis

• Published in: Mycoses Vol. 61; no. 10; pp. 770 - 776
• Main Authors: Sehgal, Inderpaul Singh, Choudhary, Hansraj, Dhooria, Sahajal, Aggarwal, Ashutosh Nath, Garg, Mandeep, Chakrabarti, Arunaloke, Agarwal, Ritesh
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.10.2018
• Subjects: Adult; Aged; Alveoli; Antibodies, Fungal - blood; Aspergillosis; Aspergillus; Aspergillus fumigatus; Aspergillus fumigatus - immunology; Aspergillus fumigatus - isolation & purification; Bronchus; Chronic Disease; chronic pulmonary aspergillosis; Diagnosis; ELISA; Female; Humans; IgG; ImmunoCap; Immunoglobulin G; Immunoglobulin G - blood; Male; Mannans - analysis; Middle Aged; Municipalities; Precipitins; Prospective Studies; Pulmonary Aspergillosis - diagnosis; Pulmonary Aspergillosis - diagnostic imaging; Pulmonary Aspergillosis - microbiology; Radiography, Thoracic; ROC Curve; Sensitivity and Specificity; Sputum; Tuberculosis; Yard waste; IgG; chronic pulmonary aspergillosis; ImmunoCap; aspergillosis; ELISA

Aspergillus fumigatus‐specific IgG is pivotal in making the diagnosis of chronic pulmonary aspergillosis (CPA). However, the cut‐off value for A. fumigatus‐specific IgG remains unknown. We included consecutive treatment‐naïve subjects with chronic cavitary pulmonary aspergillosis (CCPA, cases). The...