Acute Pain Control Challenges with Buprenorphine/Naloxone Therapy in a Patient with Compartment Syndrome Secondary to McArdle's Disease: A Case Report and Review

• Published in: Pain medicine (Malden, Mass.) Vol. 14; no. 8; pp. 1187 - 1191
• Main Authors: McCormick, Zachary, Chu, Samuel K., Chang‐Chien, George C., Joseph, Petra
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.08.2013
• Subjects: Acetaminophen - therapeutic use; Acute Pain - drug therapy; Acute Pain - etiology; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic - therapeutic use; Analgesics, Opioid - therapeutic use; Buprenorphine - therapeutic use; Buprenorphine/Naloxone; Compartment Syndrome; Compartment Syndromes - drug therapy; Compartment Syndromes - etiology; Creatine Kinase - blood; Drug Combinations; Glycogen Storage Disease Type V - complications; Humans; Hydromorphone - administration & dosage; Hydromorphone - therapeutic use; Injections, Intramuscular; Male; McArdle's Disease; Middle Aged; Naloxone - therapeutic use; Narcotic Antagonists - therapeutic use; Opioid-Related Disorders - complications; Pain management; Pain Measurement; Rhabdomyolysis; Rhabdomyolysis - etiology; Suboxone; Buprenorphine/Naloxone; Compartment Syndrome; Rhabdomyolysis; Suboxone; McArdle's Disease

Objective We report the first case of non‐iatrogentic exertional rhabdomyolysis leading to acute compartment syndrome in a patient with McArdle's disease. We describe considerations of concurrent buprenorphine/naloxone therapy during episodes of severe acute pain. Design Case report. Case Prese...