ETV5 facilitates tumor progression in head‐neck squamous cell carcinoma

• Published in: Oral diseases Vol. 30; no. 4; pp. 2004 - 2017
• Main Authors: Yu, Shijin, Ma, Zongjun, Chen, Tao, Wang, Hong, Yao, Qin, Li, Jin, Cheng, Jie
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.05.2024
• Subjects: Animals; Apoptosis; Apoptosis - genetics; Bioinformatics; Biomarkers; Cell Line, Tumor; Cell migration; Cell Movement - genetics; Cell proliferation; Cell Proliferation - genetics; Cholecystokinin; Disease Progression; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; ETS protein; ETV5; Flow cytometry; Gene Expression Regulation, Neoplastic; Head & neck cancer; Head and neck carcinoma; Head and Neck Neoplasms - genetics; Head and Neck Neoplasms - metabolism; Head and Neck Neoplasms - pathology; head neck squamous cell carcinoma; Humans; Immunohistochemistry; Mice; Mice, Nude; Neoplasm Invasiveness - genetics; prognostic biomarker; Promoter Regions, Genetic - genetics; slug; Snail Family Transcription Factors - genetics; Snail Family Transcription Factors - metabolism; Squamous cell carcinoma; Squamous Cell Carcinoma of Head and Neck - genetics; Squamous Cell Carcinoma of Head and Neck - metabolism; Squamous Cell Carcinoma of Head and Neck - pathology; Transcription Factors - genetics; Transcription Factors - metabolism; Tumorigenesis; Wound healing; prognostic biomarker; head neck squamous cell carcinoma; ETV5; slug

Objective E26 transformation‐specific (ETS) factors have emerged as key mediators underlying human tumorigenesis. Here, we sought to characterize the expression pattern, biological roles, and clinical significance of ETS Variant Transcription Factor 5 (ETV5) in head neck squamous cell carcinoma (HNS...