Ultrahigh Sensitive Detection of Tau Protein as Alzheimer's Biomarker via Microfluidics and Nanofunctionalized Optical Fiber Sensors

• Published in: Advanced photonics research Vol. 3; no. 11
• Main Authors: Chiavaioli, Francesco, Santano Rivero, Desiree, Del Villar, Ignacio, Socorro‐Leránoz, Abián B., Zhang, Xuejun, Li, Kaiwei, Santamaría, Enrique, Fernández-Irigoyen, Joaquín, Baldini, Francesco, van den Hove, Daniel L. A., Shi, Lei, Bi, Wei, Guo, Tuan, Giannetti, Ambra, Matias, Ignacio R.
• Format: Journal Article
• Language: English
• Published: Hoboken John Wiley & Sons, Inc 01.11.2022; Wiley-VCH
• Subjects: Alzheimer's disease; Amino acids; Biomarkers; biophotonic platforms; Brain; Dementia; lossy-mode resonances; Mass spectrometry; Medical imaging; microfluidics; nanofunctionalized optical fibers; Neuroimaging; Proteins; Scanning electron microscopy; Scientific imaging; Sensors; Tomography; United States > US

Alzheimer's disease (AD) is one of the most common neurodegenerative illnesses displaying the highest death rate in the elderly. However, the existing AD diagnostic system remains elusive due to lack of a technology that may ensure enough sensitivity and reproducibility, detection accuracy, and...