Gene variability in matrix metalloproteinases in patients with recurrent aphthous stomatitis

• Published in: Journal of oral pathology & medicine Vol. 49; no. 3; pp. 271 - 277
• Main Authors: Slezakova, Simona, Borilova Linhartova, Petra, Bartova, Jirina, Petanova, Jitka, Kuklinek, Pavel, Fassmann, Antonin, Dusek, Ladislav, Izakovicova Holla, Lydie
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.03.2020
• Subjects: Adult; Aged; Alleles; Aphthous stomatitis; Case-Control Studies; case‐control study; Collagen (type I); Collagenase 3; Female; Gelatinase A; Gelatinase B; Gene Frequency; Genetic factors; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Inflammatory diseases; Male; Matrix metalloproteinase; Matrix Metalloproteinases - genetics; Metalloproteinase; Middle Aged; Mucosa; Neutrophil collagenase; Polymerase chain reaction; polymorphism; Polymorphism, Single Nucleotide; recurrent aphthous stomatitis; Stomatitis; Stomatitis, Aphthous - enzymology; Stomatitis, Aphthous - genetics; Stromelysin; Stromelysin 1; matrix metalloproteinase; polymorphism; recurrent aphthous stomatitis; case-control study

Background The development of recurrent aphthous stomatitis (RAS), inflammatory disease of oral mucosa, is influenced by both environmental and genetic factors. The aim of this study was to investigate polymorphisms located in seven genes coding different types of matrix metalloproteinases (MMPs)—co...