Long noncoding RNA HOXD‐AS1 induces epithelial‐mesenchymal transition in breast cancer by acting as a competing endogenous RNA of miR‐421

• Published in: Journal of cellular biochemistry Vol. 120; no. 6; pp. 10633 - 10642
• Main Authors: Li, Yinyan, Han, Xu, Li, Qiaobei, Wang, Chunyan, Lou, Zhe, Wang, Xuemei
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.06.2019
• Subjects: Antisense RNA; Breast cancer; Cancer; Cell cycle; Cell migration; Cell proliferation; competing endogenous RNA; Deregulation; epithelial‐mesenchymal transition; Females; Function analysis; Gene expression; HOXD‐AS1; long noncoding RNA; Mesenchyme; microRNA‐421; Patients; Ribonucleic acid; RNA; Therapeutic applications; Tissues; long noncoding RNA; breast cancer; microRNA-421; HOXD-AS1; epithelial-mesenchymal transition; competing endogenous RNA

Breast cancer (BCa) is the most common malignant tumor in females. Long noncoding RNAs (lncRNAs) are deregulated in many types of human cancers, including BCa. The purpose of the present study was to examine the expression profile and biological role of HOXD cluster antisense RNA 1 (HOXD‐AS1) in BCa...