Osteoimmunological insights into the pathogenesis of ankylosing spondylitis

• Published in: Journal of cellular physiology Vol. 236; no. 9; pp. 6090 - 6100
• Main Authors: Liu, Lifei, Yuan, Yu, Zhang, Shihua, Xu, Jiake, Zou, Jun
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.09.2021
• Subjects: Ankylosing spondylitis; Arthritis; B cell; Biomedical materials; Bones; Cytokines; Immune system; Immunology; Inflammation; Lymphocytes; Lymphocytes B; Lymphocytes T; Mesenchyme; Molecular modelling; Osteogenesis; osteoimmunology; Osteolysis; Pathogenesis; skeletal system; Spine; Stem cells; T cell; B cell; T cell; ankylosing spondylitis; osteoimmunology; skeletal system
• ISSN: 0021-9541; 1097-4652; 1097-4652
• DOI: 10.1002/jcp.30313

Ankylosing spondylitis (AS) is inflammatory arthritis predominantly affecting the spine, which is involved in the disorders of both immune and skeletal systems. The exact pathogenesis of AS is not fully understood. Osteoimmunology is a new subject of study in inflammatory arthritis, in particular th...