Factors influencing medication‐taking behaviour with adjuvant endocrine therapy in women with breast cancer: A qualitative systematic review

• Published in: Journal of advanced nursing Vol. 76; no. 2; pp. 445 - 458
• Main Authors: Xu, Hui, Zhang, Xiu‐jie, Wang, Da‐qiu, Xu, Lei, Wang, Ai-ping
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.02.2020
• Subjects: adherence; Behavior modification; Breast cancer; Drugs; Efficacy; Endocrine therapy; experience; factors; Health care; medicine‐taking behaviour; nursing; Qualitative research; Risk behavior; Suffering; Systematic review; thematic synthesis; Treatment preferences; Women; Womens health; thematic synthesis; adherence; breast cancer; nursing; qualitative research; experience; systematic review; endocrine therapy; factors; medicine-taking behaviour
• DOI: 10.1111/jan.14253
• ISSN: 0309-2402; 1365-2648

Aims To explore the experience and feelings associated with the endocrine therapy treatment trajectory in women with breast cancer and what affects medication taking behaviour. Design Qualitative systematic review. Data sources Qualitative studies were extracted from PubMed, EMBASE, CINAHL, PsycINFO from inception of each database until February 2019. Review methods The systematic search method SPIDER (sample, phenomenon of interest, design, evaluation, research type) was used. Thematic synthesis of the qualitative data was used. Results A total of 478 were identified in the initial search. Only 17 articles met inclusion criteria and were included in this review. Five analytical themes and 17 descriptive subthemes were identified. Conclusions The systematic review highlights knowledge, balancing the scales, self‐efficacy and support influence medication taking behaviour to women with breast cancer. Impact The medication taking behaviour of breast cancer women can be classified into four types: acceptance/persistence, bearing/suffering, hesitation/adjustment, refusing/abandoning. The four types can switch from one to another. Medication taking behaviour is affected by knowledge, balancing the scales, self‐efficacy, and support. The medical institutions, communities, and families can gain knowledge of the treatment experiences of women to better understand medication taking behaviour and those at risk for non‐adherence. Women wanted different types and amounts of information. Healthcare providers should be aware of patient preferences and take targeted interventions to help them receive treatment. 目的 探讨患有乳腺癌女性内分泌疗法治疗轨迹的相关经历和感受,以及影响服药行为的因素。 设计 定性系统评估。 数据来源 通过 PubMed、EMBASE、CINAHL、PsycINFO 进行检索(从数据库建立之初到2019年2月),提取相关文献展开定性研究。 评估方法 采用系统搜索法SPIDER(样本、兴趣现象、设计、评价、研究类型)。定性数据采用专题综合法。 结果 初步搜索中共确定478篇相关文章。只有17篇文章符合纳入标准,因此将它们纳入本次评估之中。最终确定了5项分析主题和17项描述性次级主题。 结论 本项系统评估突出说明了个人认识,量表平衡、自我效能感和支持帮助可对患有乳腺癌女性服药行为产生影响。 影响 患有乳腺癌女性的服药行为可分为四种类型:接受/坚持、承受/痛苦、犹豫/调整、拒绝/放弃。这四种类型之间会相互转换。服药行为受个人认识、量表平衡、自我效能感和支持帮助的影响。医疗机构、社区和家庭可通过获知女性的治疗经历,来更好地了解服药行为影响因素和可能出现不依从的情况。女性希望获取不同类型和数量的信息。医疗服务提供者应了解患者的偏好,并采取有针对性的干预措施,帮助他们接受治疗。