Topical pilocarpine for xerostomia in patients with head and neck cancer treated with radiotherapy

• Published in: Oral diseases Vol. 26; no. 6; pp. 1209 - 1218
• Main Authors: Pereira, Raony Môlim de Sousa, Bastos, Mônica Danielle Ribeiro, Ferreira, Maíra Peres, Freitas, Osvaldo, Macedo, Leandro Dorigan, Oliveira, Harley Francisco, Ricz, Hilton Marcos Alvez, Motta, Ana Carolina Fragoso, Macedo, Ana Paula, Tirapelli, Camila, Pedrazzi, Vinicius
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.09.2020
• Subjects: clinical trial; Clinical trials; Head & neck cancer; head and neck cancer; Patients; Pilocarpine; Quality of life; Radiation therapy; radiotherapy; Saliva; Topical application; Xerostomia; clinical trial; pilocarpine; radiotherapy; xerostomia; head and neck cancer; quality of life

Objective To evaluate a pilocarpine spray as a treatment for xerostomia in patients treated with radiotherapy (RT) for head and neck cancer (HNC). Methods This was a placebo‐controlled, double‐blind, crossover clinical trial of patients complaining of dry mouth after RT for HNC. Forty patients were...