Advances of antitumor drug discovery in traditional Chinese medicine and natural active products by using multi‐active components combination

• Published in: Medicinal research reviews Vol. 43; no. 5; pp. 1778 - 1808
• Main Authors: Zhao, Wei, Zheng, Xiao‐Di, Tang, Paula Yun‐Zhi, Li, Hong‐Mei, Liu, Xue, Zhong, Jian‐Jiang, Tang, Ya‐Jie
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.09.2023
• Subjects: active components; Alkaloids; Antineoplastic Agents - pharmacology; antitumor drug; Cancer; drugs combination; Drugs, Chinese Herbal - adverse effects; Flavonoids; Herbal medicine; Humans; Medicine, Chinese Traditional; R&D; Research & development; Traditional Chinese medicine; traditional Chinese medicine; antitumor drug; drugs combination; active components

The antitumor efficacy of Chinese herbal medicines has been widely recognized. Leading compounds such as sterols, glycosides, flavonoids, alkaloids, terpenoids, phenylpropanoids, and polyketides constitute their complex active components. The antitumor monomers derived from Chinese medicine possess...