LncRNA MALAT1 induces colon cancer development by regulating miR‐129‐5p/HMGB1 axis

• Published in: Journal of cellular physiology Vol. 233; no. 9; pp. 6750 - 6757
• Main Authors: Wu, Qiong, Meng, Wen‐Ying, Jie, Ying, Zhao, Haijian
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.09.2018
• Subjects: Bioinformatics; Biomarkers; Cancer; Cell proliferation; Colon; Colon cancer; Colorectal cancer; HMGB1; HMGB1 protein; Intestine; MALAT1; miRNA; miR‐129‐5p; mRNA; Proteins; Ribonucleic acid; RNA; Tumor cell lines; Tumors; MALAT1; HMGB1; colon cancer; miR-129-5p

Recent studies have exhibited significant roles of lncRNAs in various tumors' development, including colon cancer. Our study focused on the biological roles of lncRNA MALAT1 in colon cancer. In our study, it was demonstrated that MALAT1 was upregulated in human colon cancer cell lines including...