Increasing acetyl‐CoA metabolism attenuates injury and alters spinal cord lipid content in mice subjected to experimental autoimmune encephalomyelitis - Chevalier, Amber C.; Rosenberger, Thad A. (Journal of neurochemistry, 2017)
Keywords: acetate; Acetates - therapeutic use; Acetic acid; Acetyl Coenzyme A - metabolism; Acetylation; acetyl‐CoA; Animal models; Animals; Behavior, Animal - drug effects; Borreliosis; Brain; Cholesterol; Choline; Chromatography, Thin Layer; Dietary supplements; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental - chemically induced; Encephalomyelitis, Autoimmune, Experimental - immunology; Encephalomyelitis, Autoimmune, Experimental - pathology; Encephalomyelitis, Autoimmune, Experimental - prevention & control; Energy reserves; Esters; Ethanolamine; Experimental allergic encephalomyelitis; fatty acid; Fatty acids; Fatty Acids - metabolism; Female; Glycoproteins; Histochemistry; Histones; Inflammation; lipid; Lipid metabolism; Lipid Metabolism - drug effects; Lipid Metabolism - physiology; Lipids; Metabolism; Mice; Mice, Inbred C57BL; Multiple sclerosis; Myelin; Myelin Sheath - metabolism; Myelin-Oligodendrocyte Glycoprotein - toxicity; myelination; Neurochemistry; Neuroprotection; Oligodendrocyte-myelin glycoprotein; Peptide Fragments - toxicity; Phosphatidylserine; Phospholipase; Phospholipase A2; Phospholipases A2 - metabolism; Protein turnover; Rodents; Spinal cord; Spinal Cord - drug effects; Spinal Cord - enzymology; Spinal cord injuries; Statistics, Nonparametric; Triglycerides - pharmacology; acetate; phospholipase; fatty acid; myelination; acetyl-CoA; lipid