The origin and evolution of emerged swine acute diarrhea syndrome coronavirus with zoonotic potential

• Published in: Journal of medical virology Vol. 95; no. 3; pp. e28672 - n/a
• Main Authors: Yu, De, Zhao, Zhuang‐Yan, Yang, Yong‐Le, Qin, Yu, Pan, Dan, Yuan, Li‐Xia, Huang, Yao‐Wei, Wang, Bin
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2023
• Subjects: alphacoronavirus; Alphacoronavirus - genetics; Animals; Chiroptera; Coevolution; Coronaviridae; Coronavirus Infections - epidemiology; Coronaviruses; Diarrhea; Diarrhea - veterinary; Disease transmission; Evolution; evolutionary analysis; Glycoproteins; interspecies transmission; Positive selection; Public health; Recombination; Rhinolophus; S gene; Spike glycoprotein; Swine; swine acute diarrhea syndrome coronavirus (SADS‐CoV); Swine Diseases - epidemiology; Variance analysis; Virology; Viruses; Vomiting; Zoonoses; swine acute diarrhea syndrome coronavirus (SADS-CoV); zoonoses; alphacoronavirus; interspecies transmission; evolutionary analysis

Swine acute diarrhea syndrome coronavirus (SADS‐CoV) is a newly discovered alphacoronavirus with zoonotic potential that causes diarrhea and vomiting mainly in piglets. Having emerged suddenly in 2017, the prevailing opinion is that the virus originated from HKU2, an alphacoronavirus whose primary h...