Sub‐second transient activated patterns to sad expressions in major depressive disorders discovered via hidden Markov model

• Published in: Journal of neuroscience research Vol. 99; no. 12; pp. 3250 - 3260
• Main Authors: Dai, Zhongpeng, Zhang, Siqi, Wang, Xinyi, Wang, Huan, Zhou, Hongliang, Tian, Shui, Chen, Zhilu, Lu, Qing, Yao, Zhijian
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2021
• Subjects: Biomarkers; Brain; Brain Mapping; Data processing; Depressive Disorder, Major - diagnosis; Emotions; Facial Expression; hidden Markov model; Humans; Information processing; Limbic system; Magnetic Resonance Imaging; Magnetoencephalography; major depressive disorders; Markov chains; Mental depression; Mental disorders; negative stimuli; Occupancy; Visual stimuli; major depressive disorders; hidden Markov model; magnetoencephalography; negative stimuli

The pathological mechanisms of major depressive disorders (MDDs) is associated with the overexpression of negative emotions, and the fast transient‐activated patterns underlying overrepresentation in depression still remain to be revealed to date. We hypothesized that the aberrant spatiotemporal att...