Dynamics of glycerine and water transport across human skin from binary mixtures

• Published in: International journal of cosmetic science Vol. 39; no. 2; pp. 165 - 178
• Main Authors: Ventura, S. A., Kasting, G. B.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.04.2017
• Subjects: Absorption; Biological effects; Biological Transport; delivery/vectorization/penetration; Desorption; Diffusion coefficient; diffusivity; Emollients; Glycerol - metabolism; Humans; moisturization; Permeability; Retention; Skin - metabolism; skin hydration; skin permeation; Sorption; Water; Water - metabolism; Water content; Water transport; diffusivity; skin permeation; moisturization; delivery/vectorization/penetration; skin hydration

Objective Skin transport properties of glycerine and water from binary mixtures contacting human skin were determined to better understand the mechanism of skin moisturization by aqueous glycerine formulations. Methods Steady‐state permeation for 3H2O and 14C‐glycerine across split‐thickness human s...