Predictors of sustained functional cure in hepatitis B envelope antigen‐negative patients achieving hepatitis B surface antigen seroclearance with interferon‐alpha–based therapy

• Published in: Journal of viral hepatitis Vol. 26; no. S1; pp. 32 - 41
• Main Authors: Li, Ming‐Hui, Yi, Wei, Zhang, Lu, Lu, Yao, Lu, Hui‐Hui, Shen, Ge, Wu, Shu‐Ling, Hao, Hong‐Xiao, Gao, Yuan‐Jiao, Chang, Min, Liu, Ru‐Yu, Hu, Lei‐Ping, Cao, Wei‐Hua, Chen, Qi‐Qi, Li, Jun‐Nan, Wan, Gang, Xie, Yao
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.07.2019
• Subjects: Antigens; chronic hepatitis B; functional cure; Hepatitis; Hepatitis B; Hepatitis B e antigen; hepatitis B e antigen negative; Hepatitis B surface antigen; hepatitis B surface antigen loss; Interferon; Patients; chronic hepatitis B; hepatitis B e antigen negative; functional cure; hepatitis B surface antigen loss; interferon

Hepatitis B surface antigen (HBsAg) loss is considered a functional cure in chronic hepatitis B (CHB). However, the durability of HBsAg loss after stopping treatment remains unknown. This study aimed to assess the sustained functional cure achieved by interferon therapy in hepatitis B envelope antig...