The utility of non‐invasive tests to assess advanced fibrosis in Asian subjects with chronic hepatitis B and concomitant hepatic steatosis

• Published in: Liver international Vol. 43; no. 5; pp. 1008 - 1014
• Main Authors: Lin, Kenneth W., Kumar, Rajneesh, Shen, Feng, Chan, Henry L.‐Y., Wong, Grace L.‐H., Kumar, Rahul, Chow, Wan Cheng, Lin, Su, Wong, Vincent W.‐S., Fan, Jian‐Gao, Goh, George B.‐B.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2023
• Subjects: Adult; advanced fibrosis; Aspartate Aminotransferases; Biomarkers; Biopsy; chronic hepatitis B; Fatty liver; Fatty Liver - complications; Fatty Liver - diagnosis; Fatty Liver - epidemiology; Female; Fibrosis; Hepatitis; Hepatitis B; Hepatitis B, Chronic - complications; Hepatitis B, Chronic - diagnosis; Hepatitis B, Chronic - pathology; Humans; Liver; Liver Cirrhosis - complications; Liver Cirrhosis - diagnosis; Liver Cirrhosis - epidemiology; Male; Morbidity; non‐alcoholic fatty liver disease; non‐invasive tests; Predictive Value of Tests; ROC Curve; Severity of Illness Index; Steatosis; Asia; chronic hepatitis B; non-alcoholic fatty liver disease; non-invasive tests; advanced fibrosis

Background Chronic hepatitis B (CHB) is endemic to Asia and is a leading cause of liver‐related morbidity. The prevalence of concomitant CHB and hepatic steatosis (HS) is increasing in Asia. Non‐invasive tests (NITs) including FIB‐4, NFS and APRI assess fibrosis in populations with a single aetiolog...