Association of statin use with Parkinson's disease: Dose–response relationship

• Published in: Movement disorders Vol. 34; no. 7; pp. 1014 - 1021
• Main Authors: Jeong, Su‐Min, Jang, Wooyoung, Shin, Dong Wook
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.07.2019; Wiley Subscription Services, Inc
• Subjects: Aged; Aged, 80 and over; Cholesterol; Cohort Studies; Databases, Factual; Dementia - drug therapy; Dementia - etiology; Dementia disorders; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects; Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology; Incidence; Male; Middle Aged; Movement disorders; National Health Programs - statistics & numerical data; Neurodegenerative diseases; Parkinson Disease - complications; Parkinson Disease - drug therapy; Parkinson's disease; Proportional Hazards Models; Risk Factors; Statin; Statins; cholesterol; Parkinson's disease; Statin

Background There have been conflicting results on the association between statin use and Parkinson's disease (PD) incidence. Objectives This study investigated the association between time‐varying status of statin use and incidence of PD while considering the dose–response relationship and tota...