Hypothalamic–pituitary function following childhood brain tumors: Analysis of prospective annual endocrine screening

• Published in: Pediatric blood & cancer Vol. 66; no. 5; pp. e27631 - n/a
• Main Authors: Lawson, Sarah A., Horne, Vincent E., Golekoh, Marjorie C., Hornung, Lindsey, Burns, Karen C., Fouladi, Maryam, Rose, Susan R.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2019
• Subjects: Adolescent; brain; Brain cancer; Brain Neoplasms - complications; Brain tumors; Child; Child, Preschool; Childhood; Children; CNS tumors; Demography; Diagnosis; Early Detection of Cancer - statistics & numerical data; Endocrine disorders; Endocrine System Diseases - diagnosis; Endocrine System Diseases - etiology; Endocrinology; Female; Follow-Up Studies; Hematology; Humans; Hypothalamic Neoplasms - diagnosis; Hypothalamic Neoplasms - etiology; Hypothalamus; late effects of cancer treatment; Male; Oncology; Patients; pediatric endocrinology; pediatric oncology; Pediatrics; Pituitary; Prognosis; Prospective Studies; Radiation; Retrospective Studies; Spinal cord; Survival Rate; Tumors; tumors; pediatric endocrinology; pediatric oncology; late effects of cancer treatment; brain; CNS tumors; endocrinology

Background Outcomes for childhood brain tumors are now associated with a five‐year survival rate of 75%. Endocrine effects of brain tumors are common, occurring in 43% of patients by 10 years from tumor diagnosis. Optimal timing of screening for endocrinopathies remains undefined. We aim to identify...